Wholesale Pure Natural Atractylodes Oli ea Lancea bakeng sa Daily Chemical Industry Herb Extract Atractylis Oil

pisthorchis viverrini (OV) -induced cholangiocarcinoma (CCA) ke mofetše o tloaelehileng pakeng tsa banna le basali, haholo-holo Thailand. Boithuto ba morao-rao bo bonts'itse hore tlhahiso ea ethanol ea AL e na le phello e thibelang ho mofuta oa liphoofolo oa OV-induced CCA ntle le chefo e hlakileng ka tsamaiso ea molomo bakeng sa matsatsi a 30 ho latela liphetho tse tsoang ho positron emission tomography-computed tomography le hamster ea banna ba Syria.7]. E le ho hlahloba phello ea AL rhizome ho motility ea mala, litoeba tse phekoloang ke atropine-, dopamine-, le 5-hydroxytryptamine (5-HT) li ile tsa amoheloa thutong. Liphetho li bontšitse hore 1 mg/kg e ntšitsoeng e ka hatella haholo ho tsoa ka mpeng e bakoang ke dopamine le ho fokotseha ha mala ka ente ea intraperitoneal. Motsoako oa 1000 mg / kg o ka thibela ho fokotseha ha mala a manyane a atropine, 'me karolo ea 500 mg / kg e ka thibela ho tsoa ha gastric e bakoang ke 5-HT le ho fokotseha ha mala a manyane.8]. Ho phaella moo, AL e sebelisitse phello e khahlanong le gastric ulcer ka mokhoa oa rat ka ho fokotseha ha li-mediators tsa ho ruruha (ke hore tumor necrosis factor-α (TNF-α), interleukin-8 (IL-8), IL-6), le prostaglandin E2 (PGE2) le ho eketseha ha epidermal growth factor (EGF) le trefoil factor2 (TFF2) [9]. Likokoana-hloko tsa fungal tse jereng mobu li fokolitse 30% ea lihlahisoa tsa matokomane [10]. Haufinyane tjena, ho ile ha tlalehoa hore ho jala lijalo le makotomane, AL e ka boela ea hatella mafu a fungal a jereng mobu ka ho thibelaFusarium oxysporumkgolo [11]. Petroleum ether (PE) e nkiloeng ho tloha ho AL e bontšitse phello e thibelang BGC-823 le SGC-7901 lisele tsa kankere ea mala ea motho. Karolo ea PE e ka baka apoptosis, ho ts'oaroa ha lisele, le liphetoho tse ka bang teng tsa mitochondrial transmembrane [12]. Tlaleho ea morao-rao e bontšitse hore tlhahiso ea MeOH ea AL e ka thibela tlhahiso ea nitric oxide (NO) ka lipopolysaccharide-stimulated murine macrophage-like RAW264.7 lisele le ho etsa hore ho be le secretion ea granulocyte-colony stimulating factor (G-CSF) liseleng tse tloaelehileng tsa colonic epithelial MCE301. NO ke radical mahala [13]. Motsoako oa ethanol oa AL o na le phello ea bohlokoa ea ho thibela lipase ka IC50 9.06 µg/mL tekong ea motho ea pancreatic lipase assay, 'me e bontšitse phello e khahlanong le botenya mofuteng oa litoeba tsa ho nona tse bakoang ke lijo tse ngata ka bongata bo phahameng ba 500 mg. /kg [14]. Li-extracts tsa metsi tse tsoang ho AL li bonts'itse ts'ebetso ea bohanyetsi khahlano le li-receptor tsa serotonin le phello ea inhibitory ho khetho ea 5-HT2A / 2C agonist 1-(2,5-dimethoxy-4-iodophenyl) -2-aminopropane-induced head-twitch response ho litoeba. [15]. Lisebelisoa tsa metsi tse tsoang ho AL li fokolitse chefo e bakoang ke triptolide ka ho theola-taolo ea polelo ea sebete ea CYP3A. Khabareng, AL e ka ntlafatsa litlamorao tse khahlanong le ho ruruha tsa triptolide. Liphuputso tsena li khothalelitse hore AL e ka thibela chefo le ho eketsa ts'ebetso ea kalafo ea triptolide ka ho kopanya.